Anti-emetic Drugs In Oncology: Pharmacology And Individualization By Pharmacogenetics

Chemotherapy-Induced Nausea and Vomiting

Key Findings

Nabilone as anti-emetic was superior to placebo, domperidone and prochlorperazine in preventing CINV, but not superior not metoclopramide or chlorpromazine. Nabilone also did not increase the benefit of 5-HTRAs as anti-emetic in CINV. The use of cannabinoids and olanzapine have been suggested as potentially useful interventions, but data from phase III clinical trials are still lacking.

Information and Links


Link: Anti-emetic Drugs In Oncology: Pharmacology And Individualization By Pharmacogenetics

Year: 2011

DOI: 10.1007/s11096-010-9454-1


Ratings

(How Ratings Work)

Chemotherapy-Induced Nausea and Vomiting — 3


Likely probability of the efficacy of cannabis for treatment of Chemotherapy-Induced Nausea and Vomiting according to the results found in this study.

Drugs Used

Nabilone